Sometimes when you are around many Mac users and everyone has a remote, say during presentations it can be annoying to have others remote controls messing with your Mac.  Or in the case of a kiosk computer, you don’t ever want a remote control to function.

To disable or block all remote controls from accessing your mac, click on the System Preferences icon.  From the System Preferences screen click on Security.

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From the Security settings window check the box next to Disable remote control infrared receiver.

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That’s all there is to it.  No remote control will now be able to work with your Mac (regardless of pairing).